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Insights to inspire Better Portfolio Decisions
Expert perspectives, research, and real-world insights to advance portfolio thinking and smarter pharma decisions.


Transparent Models, Confident Decisions: Meet the AI Model Guide
Captario’s AI Model Guide eliminates black-box fears by making complex models transparent—offering clear explanations and visuals to build trust and clarity in portfolio decisions.

Magnus Ytterstad
Jan 82 min read


From Plans to Reality: How to Model Operational Risks for Smarter Forecasting
Capturing operational risks—like delays and cost overruns—in forecasting models improves decision quality, uncovers hidden threats, and strengthens strategic planning across portfolios.

Magnus Ytterstad
Dec 19, 20242 min read


NDA Submission Sequencing
At the recent Vegas PPM conference, I shared a case study highlighting the importance of nuanced modeling for strategic decision-making. The scenario involved deciding whether to sequence NDA submissions for the two indications or file them in parallel. After completing a successful Phase 3 trial for Indication A, the team faced two options: ➡️ Wait for Indication B’s trial to finish and file both NDAs together (parallel filing). ➡️ File the NDA for Indication A immediately a

Magnus Ytterstad
Dec 16, 20242 min read


Design Your Future Pipeline: Introducing Project Generators in Captario SUM
As the holiday season approaches, I wanted to share an exciting update on something we’ve been working on at Captario: Project Generators. This is an early gift for anyone tackling pipeline renewal, closing revenue gaps, or exploring innovative investment strategies to strengthen their portfolio. Project Generators are exactly what the name suggests—a feature inside Captario SUM that allows users to generate new projects based on customizable templates. These projects are aut

Magnus Ytterstad
Dec 12, 20242 min read


Reflections on Risk
In many cases, the only risk quantified in development project investment cases is PTRS (Probability of Technical and Regulatory Success). While technical failures are leading reasons for project cancellations, other critical risks often go unaddressed. Here are three additional types of risks we discussed in the presentation: 👉 Operational Risks These include delays in timelines and increases in development costs. Timeline delays harm project value by delaying revenue and p

Magnus Ytterstad
Dec 10, 20242 min read


Making Dependencies Count: Smarter Portfolio Decisions
Captario SUM now offers centralized portfolio-level dependency modeling, helping teams manage interdependencies, toggle assumptions, and reduce risk across drug development portfolios.

Magnus Ytterstad
Dec 6, 20242 min read
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