How Simulation Turns Portfolio Strategy into Action

You’ve got three assets in the same indication—A, B, and C.

Asset A is ahead in development and could be first-in-class. B and C are earlier but look stronger on efficacy.

You want to be first to market. So A is going forward. But then what?

Over the past few months, we have been working with a biotech company to explore exactly this kind of situation. We built out four distinct strategic options—not just possible outcomes, but active choices they could make about their development path.

Should they…

🧭 Develop B and C and then pick the better one?

🔁 Push both all the way through and accept the internal competition?

🔀 Reposition one of them for a different indication altogether?

Using Captario SUM, we created fully comparable simulation models—so we could evaluate each strategy side by side on timeline, cost, risk, revenue, launches, and resource demand.

The most interesting part during this exercise has been seeing how the conversation shifts when strategy becomes tangible.

When you stop looking at what might happen and start asking what should we do—that’s when real decisions happen.